Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
How the surrounding environment affects the biosensing performance of Resonant Nanopillars arrays: under dry conditions or immersed in fluid
Año:2017
Áreas de investigación
  • Óptica, electromagnetismo,
  • Biosensores
Datos
Descripción
tIn this work we demonstrate the advantage of performing the biosensing process of a refractive indexoptical biosensor under dry conditions, in comparison with the biosensing structure immersed in fluid.We developed a biosensing experiment over a specific transducer based on resonant nanopillars (R-NPs)arrays. The optical interrogation to monitor the recognition events was firstly performed with the R-NPsin dry, only in contact with the air, and secondly with the R-NPs immersed in water. We observed asignificant enhance in the sensitivity of the biosensing curve response for the R-NPs in dry conditions,leading an improvement of the Limit of Detection (LoD) in more than one order of magnitude. These resultsare also in good correlation with 3D-Finite difference time domain simulations carried out for both fluidconditions. According to this result, any interferometric optical bio-transducer for in-situ diagnosis willimprove the sensitivity in case it can operate in dry conditions. Moreover, measuring in simple drops ofbiological samples, in dry conditions, will be a relevant issue for Point of Care Devices
Internacional
Si
JCR del ISI
Si
Título de la revista
Sensors And Actuators B-Chemical
ISSN
0925-4005
Factor de impacto JCR
4,758
Información de impacto
Datos JCR del año 2015
Volumen
DOI
10.1016/j.snb.2017.11.029
Número de revista
Desde la página
956
Hasta la página
962
Mes
NOVIEMBRE
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Miguel Holgado Bolaños (UPM)
  • Autor: Ana Lopez Hernandez (UPM)
  • Autor: Rafael Casquel Del Campo (UPM)
  • Autor: Iñaki Cornago (Cemitec)
  • Autor: Fátima Fernández (Consulting Químico Sanitario S.L.)
  • Autor: Paula Ciarruz
  • Autor: Francisco Javier Sanza Gutierrez (UPM)
  • Autor: Beatriz Santamaria Fernandez (UPM)
  • Autor: Mª Victoria Maigler López (UPM)
  • Autor: Sergio Andres Quintero Moreno (UPM)
  • Autor: Maria Fe Laguna Heras (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Grupo de Óptica Fótonica y Biofotónica (GOFB)
  • Centro o Instituto I+D+i: Centro Laser
S2i 2021 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)