Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Short-Term Effects of Binaural Beats on EEG Power, Functional Connectivity, Cognition, Gait and Anxiety in Parkinson?s Disease
Año:2017
Áreas de investigación
  • Eeg/potenciales evocados,
  • Neurociencia cognitiva,
  • Demencias seniles (alzheimer, parkinson...),
  • Ingenierías
Datos
Descripción
We applied rhythmic binaural sound to Parkinson?s Disease (PD) patients to investigate its influence on several symptoms of this disease and on Electrophysiology (Electrocardiography and Electroencephalography (EEG)). We conducted a double-blind, randomized controlled study in which rhythmic binaural beats and control were administered over two randomized and counterbalanced sessions (within-subjects repeated-measures design). Patients (n=14, age 62±6.1, stage I?III Hoehn & Yahr scale) participated in two sessions of sound stimulation for 10min separated by a minimum of 7 days. Data were collected immediately before and after both stimulations with the following results: (1) a decrease in theta activity, (2) a general decrease in Functional Connectivity (FC), and (3) an improvement in working memory performance. However, no significant changes were identified in the gait performance, heart rate or anxiety level of the patients. With regard to the control stimulation, we did not identify significant changes in the variables analyzed. The use of binaural-rhythm stimulation for PD, as designed in this study, seems to be an effective, portable, inexpensive and noninvasive method to modulate brain activity. This influence on brain activity did not induce changes in anxiety or gait parameters; however, it resulted in a normalization of EEG power (altered in PD), normalization of brain FC (also altered in PD) and working memory improvement (a normalizing effect). In summary, we consider that sound, particularly binaural-rhythmic sound, may be a co-assistant tool in the treatment of PD, however more research is needed to consider the use of this type of stimulation as an effective therapy.
Internacional
Si
JCR del ISI
Si
Título de la revista
International Journal of Neural Systems
ISSN
0129-0657
Factor de impacto JCR
6,333
Información de impacto
Datos JCR del año 2016
Volumen
28
DOI
10.1142/S0129065717500551
Número de revista
5
Desde la página
1
Hasta la página
16
Mes
SIN MES
Ranking
Q1
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Gerardo Miguel Galvez Garcia (UPM)
  • Autor: Manuel Recuero Lopez (UPM)
  • Autor: Leonides Canuet Delis (UPM)
  • Autor: Francisco del Pozo Guerrero (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Investigación en Instrumentación y Acústica Aplicada (I2A2)
  • Departamento: Ingeniería Mecánica
  • Departamento: Tecnología Fotónica y Bioingeniería
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