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Descripción
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| The major milk allergen Bos d 5 is a lipocalin and can be loaded with quercetin, a flavonoid with a great affinity to iron. We previously demonstrated in vitro that the loading of Bos d 5 with such a ligand is decisive for induction of immune tolerance. Here, we addressed the in vivo relevance of this observation by nasal allergic sensitization of BALB/c mice using unloaded (apo?) or quercetin?iron?loaded (holo?) Bos d 5, and further elucidated a potential mechanistic role of the aryl hydrocarbon receptor (AhR) pathway. | |
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Internacional
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Si |
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Nombre congreso
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European Academy of Allergy and Clinical Immunology (EAACI), congress 2018. |
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Tipo de participación
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960 |
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Lugar del congreso
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Revisores
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Si |
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ISBN o ISSN
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0105-4538 |
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DOI
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Fecha inicio congreso
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26/05/2018 |
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Fecha fin congreso
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30/05/2018 |
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Desde la página
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17 |
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Hasta la página
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17 |
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Título de las actas
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Special Issue:Abstracts from the European Academy of Allergy and Clinical Immunology Congress, 26?30 May 2018, Munich, Germany |