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Descripción
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| We report the application of optical slot-waveguide micro-ring resonators to a label-free surface binding assay of protein concentration. We employ a fabrication method that enables the combination of integrated optical systems with on-chip fluid handling, without compromising the functionality of either part. Utilizing a selective isotropic plasma etch of a sacrificial chromium etch-stop layer, fluidic connections are made down to buried nanostructured optical sensing elements in a controlled manner. Slot-waveguides are a recent development in the field of integrated optics. They allow the concentration of light in a sub wavelength low refractive index slot running along the axis of the guide. Since biological samples are water based, and water has a low index compared to solids, this new waveguide type is of particular interest for refractive index biosensing. | |
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Internacional
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Si |
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Nombre congreso
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International Label-Free Biosensing Workshop |
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Tipo de participación
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960 |
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Lugar del congreso
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Holanda |
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Revisores
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Si |
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ISBN o ISSN
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0000000000 |
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DOI
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Fecha inicio congreso
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08/04/2008 |
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Fecha fin congreso
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09/04/2008 |
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Desde la página
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1 |
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Hasta la página
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1 |
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Título de las actas
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ABSTRACT |