|
Descripción
|
|
|---|---|
| In this work we propose an image registration algorithm to automatically fit protein atomic domain models into medium-resolution three-dimensional electron microscopy reconstructions (3D-EM map). The approach employs a flexible registration algorithm whose optimizer controls the generation of stereo-chemically correct models from a given reference domain belonging to a super-family of proteins. The proposed algorithm generates models automatically in the correct direction until the optimizer converges to the best fitted model. A local gradient optimizer is employed for this task. Mutual Information is used as an alternative to Cross Correlation Coefficient. An additional rigid registration that uses a local gradient optimization is applied between each generated model and the 3D-EM map. | |
|
Internacional
|
Si |
|
Nombre congreso
|
5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI 2008) |
|
Tipo de participación
|
960 |
|
Lugar del congreso
|
Paris |
|
Revisores
|
Si |
|
ISBN o ISSN
|
978-1-4244-2003-2 |
|
DOI
|
|
|
Fecha inicio congreso
|
14/05/2008 |
|
Fecha fin congreso
|
17/05/2008 |
|
Desde la página
|
983 |
|
Hasta la página
|
986 |
|
Título de las actas
|
Proceedings of 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. |