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Descripción
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| This lecture starts with the definition of tomographic imaging and the two main modalities addressed: PET and MRI. The emission tomography will be introduced and followed by the principles of image reconstruction from projections, sampling requirements and quantitative aspects (spatial resolution, sensitivity, photon attenuation, image noise). The principles of PET systems (coincidence detectors, spatial resolution, detector systems, sensitivity, true, scatter and accidental coincidence events, dead-time, signal-to-noise ratio, time of flight) and MRI cameras (quantum properties of nuclear spins, radio-frequency excitation properties, tissue relaxation properties, magnetic field strength and gradients, timing of gradients, radio-frequency pulses, and signal detection) will be presented. After this first section, the lecture will focus on the design characteristics and the performance of today¿s modern PET scanners. The different architectures will be discussed (block detectors with pixelated crystals, continuous crystals coupled to position-sensitive photomultiplier tubes, semiconductor detectors, etc.) and the limitations, along with the potential further developments in the field will be presented. The focus will be maintained on PET systems for brain imaging. In continuation, the combined PET/CT scanners will be introduced and the concept of hybrid imaging will be presented. The discussion will be then shifted to address the issue of MRI camera design (main magnet, gradient coils, radio-frequency coils, contrast enhancement and image formation) and specialized MRI scans, such as diffusion tensor imaging, functional MRI, MR spectroscopy, etc.). The last section of the lecture will be then focused on the issue of the very recent developments in research towards a combined three-dimensional scanner that can concurrently perform PET and MRI acquisitions. The main applications to date for concurrent PET/MRI are namely preclinical animal imaging and brain imaging. At the end of this lecture, the audience will be able to understand current state-of-the-art PET and MRI technologies for brain imaging, as well as learn about the efforts worldwide in research and development towards the realization of a hybrid PET/MRI system for brain imaging. | |
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Internacional
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Si |
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Nombre congreso
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Emerging Technologies in Biomedicine ¿Advanced Methods for the Estimation of Human Brain Activity and Connectivity; |
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Entidad organizadora
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University of Patras |
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Nacionalidad Entidad
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GRECIA |
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Lugar/Ciudad de impartición
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Patras |
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Fecha inicio
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30/06/2008 |
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Fecha fin
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04/07/2008 |