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Descripción
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| Diffusion MRI is a powerful methodology for the measurement of the diffusional motion of water molecules in tissue. The most outstanding and promising applications of dMRI belong to the field of brain research and clinical practice (brain mapping, connectivity and tractography algorithms development, ischemia diagnosis, early evidences of pathologies such as schizophrenia and Alzheimer¿s disease...). Although its background lies on the random Brownian motion due to thermal energy, the underlying tissue microstructure yields anisotropic diffusion, so that this technique provides useful information about the tissue geometric organization and composition, which determines the scatter pattern of water particles in tissue, as it is well documented ([1-2]). Recent models have attempted to relate both the self¿diffusion of water molecules and the underlying white matter microstructural features, where the orientation of the axonal bundles is assumed to be known a priori. It limits the application field to ex¿vivo experiments. Here we approach an extension on a former model by including directional heterogeneity in the axonal distribution based on a spherical harmonic decomposition of the fibres orientation distribution function (ODF). | |
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Internacional
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Si |
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Nombre congreso
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12th Congress of the European Federation of Neurological Societies |
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Tipo de participación
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960 |
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Lugar del congreso
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Madrid |
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Revisores
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Si |
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ISBN o ISSN
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1351-5101 |
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DOI
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Fecha inicio congreso
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23/08/2008 |
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Fecha fin congreso
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26/08/2008 |
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Desde la página
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299 |
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Hasta la página
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299 |
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Título de las actas
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European Journal of Neurology, vol. 15, suppl. 3 |