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Memorias de investigación
Capítulo de libro:
On breathing motion compensation in myocardial perfusion imaging
Áreas de investigación
  • Industria electrónica
we proposed a new scheme for breathing motion compensation in MRI perfusion studies based on non-rigid registration. In order to reduce the influence of the change of intensity, which is induced by the contrast agent as it passes through the both heart ventricles and the myocardium, we used a serial registration scheme where only subsequent images of the series are registered. In addition, we have introduced a new image similarity measure that is based on normalized gradient fields and was improved over the previous proposal in (Haber and Modersitzki, 2005). This measure is of a very local nature, and therefore, well suited to obtain non-rigid registration for images with local contrast change, as it is the case in myocardial perfusion MRI. Our experiments show that using this measure alone yields a good registration only for the images of the series that exhibit a high contrast and, hence, strong gradients in the regions of interest. When the intensity contrast is low, small registration errors may occur and, because of the serial registration scheme, these errors accumulate resulting an increasing misalignment over the series time course. We were able to improve these results by combining the normalized gradient field based cost function with the sum of squared differences, so that the first would take precedence in regions with high contrast and, hence, strong gradients, while the latter ensures a steady registration in areas with low contrast and, therefore, small gradients.
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Título del Libro
New Developments in Biomedical Engineering
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Esta actividad pertenece a memorias de investigación
  • Autor: Gert Wöllny . (UPM)
  • Autor: Maria Jesus Ledesma Carbayo (UPM)
  • Autor: Andres de Santos Lleo (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Tecnología de imágenes biomédicas
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Ingeniería Electrónica
S2i 2023 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)