Memorias de investigación
Ponencias en congresos:
A model for generating synthetic dendrites of cortical neurons
Año:2010
Áreas de investigación
  • Inteligencia artificial
Datos
Descripción
One of the main challenges in neuroscience is to define the detailed structural design of the nervous system. This challenge is one of the first steps towards understanding how neural circuits contribute to the functional organization of the nervous system. In the cerebral cortex pyramidal neurons are key elements in brain function as they represent the most abundant cortical neuronal type and the main source of cortical excitatory synapses. Therefore, many researchers are interested in the analysis of the microanatomy of pyramidal cells since it constitutes an excellent tool for better understanding cortical processing of information. Computational models of neuronal networks based on real cortical circuits have become useful tools for studying certain aspects of the functional organization of the neocortex. Neuronal morphologies (morphological models) represent key features in these functional models. For these purposes, synthetic or virtual dendritic trees can be generated through a morphological model of a given neuronal type based on real morphometric parameters obtained from intracellularly-filled single neurons. This paper presents a new method to construct virtual dendrites by means of sampling a branching model that represents the dendritic morphology. This method has been contrasted using complete basal dendrites from 374 layer II/III pyramidal neurons of the mouse neocortex.
Internacional
Si
Nombre congreso
IEA/AIE'10 Proceedings of the 23rd international conference on Industrial engineering and other applications of applied intelligent systems
Tipo de participación
960
Lugar del congreso
Revisores
Si
ISBN o ISSN
3-642-13032-1
DOI
Fecha inicio congreso
01/06/2010
Fecha fin congreso
04/06/2010
Desde la página
129
Hasta la página
138
Título de las actas
A model for generating synthetic dendrites of cortical neurons
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Jose Maria Peña Sanchez UPM
  • Participante: Jaime Fernández
  • Participante: Laura Fernández
  • Participante: Ruth Benavides-Piccione
  • Participante: Inmaculada Balleteros-Yañez
  • Participante: Javier DeFelipe
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: COMPUTATIONAL INTELLIGENCE GROUP
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB