Observatorio de I+D+i UPM

Memorias de investigación
Capítulo de libro:
Computer assisted identification, segmentation and quantification of synapses in the cerebral cortex
Año:2010
Áreas de investigación
  • Informática aplicada
Datos
Descripción
Synapses are key elements in the organization of nervous circuits. Obtaining serial images from large samples of nervous tissue in an automated manner is now possible through combined focused ion beam milling and scanning electron microscopy. However, the identification, 3D reconstruction and quantification of synapses within these samples are labor intensive procedures that require continuous user intervention. We have developed a software tool to automatically perform the segmentation of synapses in a reconstructed 3D volume of the cerebral cortex, thereby greatly facilitating and accelerating these processes. The tool is interactive, allowing the user to supervise the segmentation process, to modify the appropriate parameters and to validate the results. It is also modular to enable new functions to be implemented as needed. We have also ensured it has a user friendly interface and that it is portable, making it accessible to a wide range of potential users.
Internacional
Si
DOI
Edición del Libro
0
Editorial del Libro
Springer Verlag
ISBN
978-3-642-13032-8
Serie
LNCS
Título del Libro
Trends in Applied Intelligent Systems
Desde página
112
Hasta página
118
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Angel Rodriguez Mtnez.de Bartolome (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Departamento: Tecnología Fotónica
S2i 2021 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)