Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
NRT/PTR transporters essential for allocation of glucosinolate defense compounds to seeds.
Year:2012
Research Areas
  • Plants and animal biology and ecology
Information
Abstract
In plants, transport processes are important for the reallocation of defence compounds to protect tissues of high value, as demonstrated in the plant model Arabidopsis, in which the major defence compounds, glucosinolates, are translocated to seeds on maturation. The molecular basis for long-distance transport of glucosinolates and other defence compounds, however, remains unknown. Here we identify and characterize two members of the nitrate/peptide transporter family, GTR1 and GTR2, as high-affinity, proton-dependent glucosinolate-specific transporters. The gtr1?gtr2 double mutant did not accumulate glucosinolates in seeds and had more than tenfold over-accumulation in source tissues such as leaves and silique walls, indicating that both plasma membrane-localized transporters are essential for long-distance transport of glucosinolates. We propose that GTR1 and GTR2 control the loading of glucosinolates from the apoplasm into the phloem. Identification of the glucosinolate transporters has agricultural potential as a means to control allocation of defence compounds in a tissue-specific manner.
International
Si
JCR
Si
Title
Nature
ISBN
0028-0836
Impact factor JCR
36,101
Impact info
Datos JCR del año 2010
Volume
488
Journal number
From page
531
To page
534
Month
AGOSTO
Ranking
Participants
  • Autor: Hussam Hassan Nour-Eldin (University of Copenhagen, Denmark)
  • Autor: Tonni Grube Andersen (University of Copenhagen, Denmark)
  • Autor: Meike Burow (University of Copenhagen, Denmark)
  • Autor: Svend Roesen Madsen (University of Copenhagen, Denmark)
  • Autor: Morten Egevang Jørgensen (University of Copenhagen, Denmark)
  • Autor: Carl Erik Olsen (University of Copenhagen, Denmark)
  • Autor: Ingo Dreyer . (UPM)
  • Autor: Rainer Hedrich (Universität Würzburg, Germany)
  • Autor: Dietmar Geiger (Universität Würzburg, Germany)
  • Autor: Barbara Ann Halkier (University of Copenhagen, Denmark)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Redes Reguladoras del Desarrollo y Respuesta a Estrés en Plantas
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)