Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
P-medicine: A solution for translational research?
Year:2012
Research Areas
  • Information technology and adata processing
Information
Abstract
The nature of healthcare is changing from reactive to preventive. These changes are catalysed by a new approach to disease, which focuses on integrated diagnosis, treatment and prevention in individuals. Molecular biology and information technology are the main drivers in this process. The question is how such a translational approach can be implemented in daily clinical care of patients. Method: Multi-level data collection within clinico-genomic trials and interdisciplinary analysis by clinicians, molecular biologists and others involved in life science is mandatory to further improve the outcome of cancer patients. For that purpose p-medicine, an integrated project, funded under the 7th Framework Program of the EU (project n° 270089) started to facilitate translational research in three cancer domains. These are nephroblastoma, acute lymphoblastic leukaemia and breast cancer. Result: p-medicine is developing an integrated IT infrastructure to gain access to distributed data sources in a routine, transparent way, following appropriate anonymization and security procedures and enabling the building of tools and models based on user needs and requirements. These tools are intended to facilitate the run of clinical trials, to support physicians in their decisions toward patient treatment, to empower patients, to run system biology driven cancer models in the computer (in silico oncology) and to mine data from literature for knowledge discovery. Scenarios and examples of such tools will be demonstrated. Conclusion: The p-medicine infrastructure is able to address demanding needs in translational research. To sustain a self-supporting infrastructure realistic use cases and validated tools need to be built that will demonstrate tangible results for clinicians.
International
Si
JCR
Si
Title
Paediatric Blood & Cancer
ISBN
1545-5017
Impact factor JCR
1,891
Impact info
Volume
Journal number
From page
1101
To page
1101
Month
SIN MES
Ranking
Participants
  • Autor: Alberto Anguita Sanchez (UPM)
  • Autor: N. Graf
  • Autor: A. Bucur
  • Autor: D. Burke
  • Autor: B. Claerhout
  • Autor: P. Coveney
  • Autor: A. d'Onofrio
  • Autor: N. Forgo
  • Autor: C. Hahn
  • Autor: J. Hintz
  • Autor: B. Jefferys
  • Autor: S. Kiefer
  • Autor: K. Marias
  • Autor: G. McVie
  • Autor: C. Ohmann
  • Autor: A. Persidis
  • Autor: J. Pukacki
  • Autor: S. Rossi
  • Autor: S. Ruping
  • Autor: U. Schwarz
  • Autor: G. Stamatakos
  • Autor: M. Stanulla
  • Autor: H. Stenzhorn
  • Autor: Y. Tanaka
  • Autor: M. Taylor
  • Autor: M. Tsiknakis
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Grupo de Informática Biomédica (GIB)
  • Departamento: Inteligencia Artificial
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)