Observatorio de I+D+i UPM

Memorias de investigación
Patents:
Method and means for diagnosing and treating allergy
Year:2013
Research Areas
  • Molecular, cellular and genetic biology
Information
Abstract
The present invention relates to the use of neutrophil gelatinase-associated lipocalin (NGAL=LCN2=24p3) as a diagnostic tool for alelrgy and as a therapeutic method of treating, reducing, or ameliorating clinical manifestations of allergic disease. The invention includes measurement of NGAL levels in body fluids such as serum/plasma/saliva/blood and urin to determine sensitization state in allergic human and pet individuals. Moreover, it includes administering to the patient NGAL or lipocalin allergens in an amount effective to treat, reduce or ameliorate allergic disease. A siderophore can be co-administered with the NGAL or lipocalin allergen. The invention also relates to administering a siderophore-iron complex for allergen immunotherapy.
International
Si
Status
Solicitada
application number
EP 14150965.3.
under exploitation
No
Licensee/s
Date
17/07/2013
Owner
Participants
  • Autor: Araceli Diaz Perales (UPM)
  • Autor: Luis Fernandez Pacios (UPM)
  • Autor: Cristina Gomez Casado (UPM)
  • Autor: F Roth-Walter
  • Autor: E Jensen-Jarolim
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Biotecnología de Proteínas Vegetales
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