Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
SignWALLing: Signals Derived from the Plant Cell Wall Regulate Arabidopsis Innate Immunity
Year:2013
Research Areas
  • Agriculture
Information
Abstract
The traditional view of the cell wall as a passive barrier has evolved to a new concept that considers the wall as a dynamic structure that regulates both constitutive and inducible defence responses. The activation of plant innate immune system can be triggered by microbe-associated molecular patterns from the pathogens, but also by damaged-associated molecular patterns (DAMPs), such as molecules released from plant cell walls upon pathogen infection or wounding. In line with this cell wall function in regulating plant innate immunity, we have identified novel protein regulators of Arabidopsis resistance to necrotrophic fungi that may be involved in the control of cell wall integrity and activation of DAMP-mediated immunity. Among these regulators are the ERECTA (ER) Receptor Protein Kinase, the ? heterodimer of the heterotrimeric G protein (AGB1/AGG1(AGG2)) and the recently characterised ELK2 gene, which encodes a Mitogen-Activated Protein Kinase Kinase Kinase (MAP3K) functioning downstream ER. Remarkably, plants expressing a constitutive active form of ELK2 show a broad-spectrum resistance to necrotropic and biotrophic fungi and bacteria, further indicating that ELK2 is a key regulator of Arabidopsis immune responses. Genetic analyses revealed that ELK2 MAP3K is not a component of the downstream signalling regulated by CERK1 and FLS2 receptor kinases proteins. Like er, agb1, and agg1 agg2 mutants, elk2 showed a mis-regulation of cell wall-associated genes and alterations in cell wall composition/structure compared with those of wild-type plants. All these data suggest that remodelling of plant cell wall structure and the production of wall-derived DAMPs would be an efficient strategy for the regulation of Arabidopsis resistance to pathogens.
International
Si
Congress
Keystone Symposia. Plant immunity: Pathways and translation
960
Place
Montana (USA)
Reviewers
Si
ISBN/ISSN
00-0000-000-0
Start Date
07/04/2013
End Date
12/04/2013
From page
1
To page
1
Keystone Symposia. Plant immunity: Pathways and translation
Participants
  • Autor: Antonio Molina Fernandez (UPM)
  • Autor: Lucia Jorda Miro (UPM)
  • Autor: Sara Sopeña Torres (UPM)
  • Autor: Eva Miedes Vicente (UPM)
  • Autor: Andrea Sánchez Vallet (UPM)
  • Autor: Viviana Pamela Escudero Welsch (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Interacciones Moleculares Planta-Patógeno
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología
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