Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Branching angles of pyramidal cell dendrites follow common geometrical design principles in different cortical areas
Year:2014
Research Areas
  • Artificial intelligence
Information
Abstract
Unraveling pyramidal cell structure is crucial to understanding cortical circuit computations. Although it is well known that pyramidal cell branching structure differs in the various cortical areas, the principles that determine the geometric shapes of these cells are not fully understood. Here we analyzed and modeled with a von Mises distribution the branching angles in 3D reconstructed basal dendritic arbors of hundreds of intracellularly injected cortical pyramidal cells in seven different cortical regions of the frontal, parietal, and occipital cortex of the mouse. We found that, despite the differences in the structure of the pyramidal cells in these distinct functional and cytoarchitectonic cortical areas, there are common design principles that govern the geometry of dendritic branching angles of pyramidal cells in all cortical areas.
International
Si
JCR
Si
Title
Scientific Reports
ISBN
2045-2322
Impact factor JCR
2,927
Impact info
Datos JCR del año 2012
Volume
4
Journal number
5909
From page
1
To page
7
Month
SIN MES
Ranking
Participants
  • Autor: Maria Concepcion Bielza Lozoya (UPM)
  • Autor: Ruth Benavides Piccione (UPM)
  • Autor: Pedro Luis Lopez Cruz (UPM)
  • Autor: Pedro Maria Larrañaga Mugica (UPM)
  • Autor: Javier De Felipe Oroquieta (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Computational Intelligence Group
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Inteligencia Artificial
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)