Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
3D segmentations of neuronal nuclei from confocal microscope image stacks
Year:2013
Research Areas
  • Biomedicine
Information
Abstract
In this paper, we present an algorithm to create 3D segmentations of neuronal cells from stacks of previously segmented 2D images. The idea behind this proposal is to provide a general method to reconstruct 3D structures from 2D stacks, regardless of how these 2D stacks have been obtained. The algorithm not only reuses the information obtained in the 2D segmentation, but also attempts to correct some typical mistakes made by the 2D segmentation algorithms (for example, under segmentation of tightly-coupled clusters of cells). We have tested our algorithm in a real scenario?the segmentation of the neuronal nuclei in different layers of the rat cerebral cortex. Several representative images from different layers of the cerebral cortex have been considered and several 2D segmentation algorithms have been compared. Furthermore, the algorithm has also been compared with the traditional 3D Watershed algorithm and the results obtained here show better performance in terms of correctly identified neuronal nuclei.
International
Si
JCR
Si
Title
Frontiers in Neuroanatomy
ISBN
1662-5129
Impact factor JCR
4,058
Impact info
Volume
7
Journal number
From page
49
To page
59
Month
DICIEMBRE
Ranking
Participants
  • Autor: Lidia Alonso Nanclares (UPM)
  • Autor: Javier De Felipe Oroquieta (UPM)
Research Group, Departaments and Institutes related
  • Creador: Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
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Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)