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Memorias de investigación
Research Publications in journals:
Host resistance selects for traits unrelated to resistance-breaking that affect fitness in a plant virus
Year:2014
Research Areas
  • Virology,
  • Plant disease
Information
Abstract
The acquisition by parasites of the capacity to infect resistant host genotypes, that is, resistance-breaking, is predicted to be hindered by across-host fitness trade-offs. All analyses of costs of resistance-breaking in plant viruses have focused on within-host multiplication without considering other fitness components, which may limit understanding of virus evolution. We have reported that host range expansion of tobamoviruses on L-gene resistant pepper genotypes was associated with severe within-host multiplication penalties. Here, we analyze whether resistance-breaking costs might affect virus survival in the environment by comparing tobamovirus pathotypes differing in infectivity on L-gene resistance alleles. We predicted particle stability from structural models, analyzed particle stability in vitro, and quantified virus accumulation in different plant organs and virus survival in the soil. Survival in the soil differed among tobamovirus pathotypes and depended on differential stability of virus particles. Structure model analyses showed that amino acid changes in the virus coat protein (CP) responsible for resistance-breaking affected the strength of the axial interactions among CP subunits in the rod-shaped particle, thus determining its stability and survival. Pathotypes ranked differently for particle stability/survival and for within-host accumulation. Resistance-breaking costs in survival add to, or subtract from, costs in multiplication according to pathotype. Hence, differential pathotype survival should be considered along with differential multiplication to understand the evolution of the virus populations. Results also show that plant resistance, in addition to selecting for resistance-breaking and for decreased multiplication, also selects for changes in survival, a trait unrelated to the hostâ?pathogen interaction that may condition host range expansion.
International
Si
JCR
Si
Title
Molecular Biology And Evolution
ISBN
0737-4038
Impact factor JCR
14,308
Impact info
Volume
31
Journal number
From page
928
To page
939
Month
SIN MES
Ranking
Participants
  • Autor: Aurora Fraile Perez (UPM)
  • Autor: Jean Michel Hily (UPM)
  • Autor: Jesus Israel Pagan Muñoz (UPM)
  • Autor: Luis Fernandez Pacios (UPM)
  • Autor: Fernando Garcia-Arenal Rodriguez (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Patología Vegetal
  • Departamento: Sistemas y Recursos Naturales
  • Departamento: Biotecnología - Biología Vegetal
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