Memorias de investigación
Artículos en revistas:
Noninvasive prediction of shunt operation outcome in idiopathic normal pressure hydrocephalus
Año:2015
Áreas de investigación
  • Ciencias naturales y ciencias de la salud
Datos
Descripción
Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by gait disturbance, cognitive deterioration and urinary incontinence in elderly individuals. These symptoms can be improved by shunt operation in some but not all patients. Therefore, discovering predictive factors for the surgical outcome is of great clinical importance. We used normalized power variance (NPV) of electroencephalography (EEG) waves, a sensitive measure of the instability of cortical electrical activity, and found significantly higher NPV in beta frequency band at the right fronto-temporo-occipital electrodes (Fp2, T4 and O2) in shunt responders compared to non-responders. By utilizing these differences, we were able to correctly identify responders and non-responders to shunt operation with a positive predictive value of 80% and a negative predictive value of 88%. Our findings indicate that NPV can be useful in noninvasively predicting the clinical outcome of shunt operation in patients with iNPH.
Internacional
Si
JCR del ISI
Si
Título de la revista
Scientific Reports
ISSN
2045-2322
Factor de impacto JCR
5,578
Información de impacto
Volumen
5
DOI
10.1038/srep07775
Número de revista
5
Desde la página
7775
Hasta la página
7780
Mes
ENERO
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Leonides Canuet Delis UPM
  • Autor: Aoki Yasunori
  • : Hiroaki Kazui Hiroaki Kazui
  • Autor: Toshihisa Tanaka
  • Autor: Ryouhei Ishii
  • Autor: Tamiki Wada
  • Autor: Masahiro Hata
  • Autor: Themistoklis Katsimichas
  • Autor: Toshimitsu Musha
  • Autor: Haruyasu Matsuzaki
  • Autor: Kaoru Imajo
  • Autor: Hideki Kanemoto
  • Autor: Tetsuhiko Yoshida
  • Autor: Keiko Nomura
  • Autor: Kenji Yoshiyama
  • Autor: Masao Iwase
  • Autor: Masatoshi Takeda
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Tecnologías para Ciencias de la Salud
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Tecnología Fotónica y Bioingeniería