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Memorias de investigación
Capítulo de libro:
Monitoring Parkinson?s Disease from Phonation Improvement by Log Likelihood Ratios
Año:2015
Áreas de investigación
  • Ciencias naturales y ciencias de la salud,
  • Ingenierías
Datos
Descripción
Abstract: Parkinson's Disease (PD), contrary to other neurodegenerative diseases, supports certain treatments which can improve patients' conditions or at least mitigate disease effects. Treatments, either pharmacological, surgical or rehabilitative need longitudinal monitoring of patients to assess the progression or regression of thier condition, to optimize resources and benefits. As it is well known, PD leaves important marks in phonation, thus correlates obtained from spoken recordings taken at periodic intervals may be used in longitudinal monitoring of PD. The most preferred correlates are mel-cepstral coefficients, distortion features (jitter, shimmer, HNR, PPE, etc.), tremor indicators, or biomechanical coefficients. Feature templates estimated from each periodic evaluation have to be compared to establish potential progression or regression. The present work is devoted to propose a comparison framework based on Log Likelihood Ratios. This methodology shows to be very sensitive and allows a three-band based comparison: pre-treatment status vs post-treatment status in reference to a control subject or to a control population. Results from a database of eight male patients recorded weekly during a month are shown with comments regarding their severity condition. The conclusions derived show that several distortion, biomechanical and tremor features are quite relevant in monitoring PD phonation.
Internacional
Si
DOI
10.1109/IWOBI.2015.7160152
Edición del Libro
1
Editorial del Libro
IEEE
ISBN
978-1-4673-7846-8
Serie
Título del Libro
Bioinspired Intelligence (IWOBI), 2015 4th International Work Conference on
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1
Hasta página
6
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Pedro Gomez Vilda (UPM)
  • Autor: Carlos Alfredo Lazaro Carrascosa (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Arquitectura y Tecnología de Sistemas Informáticos
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