Descripción
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Breathing is a primal neural process by which O2, CO2 and pH are regulated. Brainstem neural circuits controlling breathing are organized as serially arrayed networks connected by both chemical and electrical synapses. Connexin-36 (Cx36) is the principal component of electrical synapses between inhibitory neurons of the rhythmogenic Bötzinger and pre-Bötzinger complexes and the CO2/pH chemosensitive retrotrapezoid nucleus. The expression pattern of Cx36 is developmentally regulated: it is absence at newborn, reaches maximum at postnatal day 15 (P15) and then it decays progressively with the age. To elucidate the role played by Cx36 synapses in the central respiratory center, we investigate here the respiratory phenotype of mice lacking Cx36. | |
Internacional
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No |
Nombre congreso
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XV Congreso Nacional Sociedad Española de Neurociencia |
Tipo de participación
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960 |
Lugar del congreso
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Oviedo |
Revisores
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Si |
ISBN o ISSN
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0212-1611 |
DOI
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Fecha inicio congreso
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25/09/2013 |
Fecha fin congreso
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27/09/2013 |
Desde la página
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231 |
Hasta la página
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232 |
Título de las actas
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http://www.tilesa.es/www.senc2013.com/abstracts/files/assets/basic-html/page1.html |