Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Luenberger observer with nonlinear structure applied to diabetes type 1
Year:2018
Research Areas
  • Electronic technology and of the communications
Information
Abstract
In this work a Luenberger observer (LO) for type 1 diabetes is established using the Hovorka?s model (HM). The HM is linearized around an operating point and the eigenvalues are calculated. The LO is designed relocating the HM eigenvalues through the Ackermann?s methodology for linear observers where the proposed LO keeps the nonlinear structure of the model system. The LO is parameterized and tuned with the mean from six virtual patients of HM. Once the observer performance is reliable estimating the state space variables for HM, the virtual patients are changed by patients of Bergman?s model in order to test the observer behavior under unknown dynamics. These estimated variables constitute the ones corresponding to HM. The variables are estimated by the data computational processing which correspond to the insulin (input) and glucose (output) of the virtual patients. The estimated variables by the LO are very similar for virtual patients generated by both models, where the parameter FIT is used to quantify the performance of the observer. The computational implementation of the LO is useful tool to estimate the unmeasured variables in diabetic patients so they can be used in the artificial pancreas.
International
Si
JCR
No
Title
International Journal of Combinatorial Optimization Problems and Informatics
ISBN
2007-1558
Impact factor JCR
Impact info
Volume
9
Journal number
1
From page
68
To page
80
Month
SIN MES
Ranking
Participants
  • Autor: Gema Garcia Saez (UPM)
  • Autor: Maria Elena Hernando Perez (UPM)
  • Autor: Agustin Rodriguez Herrero (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Grupo de Bioingeniería y Telemedicina
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Tecnología Fotónica y Bioingeniería
  • Departamento: Ingeniería Telemática y Electrónica
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)