Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
The major birch pollen allergen Bet v 1a displays reduced allergenic potential with retinoic acid in the pocket
Year:2018
Research Areas
  • Natural sciences and health sciences,
  • Molecular, cellular and genetic biology,
  • Biological sciences
Information
Abstract
Bet v 1a represents the most typical allergen prototype. Its isoform Bet v 1d, however, is a hypoallergen despite of being structurally homologous. We hypothesized that the ligandbinding capacity of these lipocalin?like molecules could discriminate their level of allergenicity. We investigated thus whether the active vitamin A metabolite retinoic acid (RA) can bind to both isoforms, and how this affects their allergenicity in vitro.
International
Si
Congress
European Academy of Allergy and Clinical Immunology (EAACI), congress 2018
970
Place
Reviewers
Si
ISBN/ISSN
0105-4538
Start Date
26/05/2018
End Date
30/05/2018
From page
448
To page
448
Special Issue:Abstracts from the European Academy of Allergy and Clinical Immunology Congress, 26?30 May 2018, Munich, Germany
Participants
  • Autor: Luis Fernandez Pacios (UPM)
  • Autor: K Hufnagl
  • Autor: N Braun
  • Autor: S Wagner
  • Autor: M Wiederstein
  • Autor: M Wallner
  • Autor: G Hofstetter
  • Autor: F Roth-Walter
  • Autor: E Jensen-Jarolim
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Biotecnología Vegetal
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología - Biología Vegetal
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