Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Analysis and Interpretation of Dynamic FDG-PET Oncological Studies using Data Reduction Techniques
Año:2007
Áreas de investigación
  • Industria electrónica
Datos
Descripción
Background: Dynamic positron emission tomography studies produce a large amount of image data, from which clinically useful parametric information can be extracted using tracer kinetic methods. Data reduction methods can facilitate the initial interpretation and visual analysis of these large image sequences and at the same time can preserve important information and allow for basic feature characterization. Methods: We have applied principal component analysis to provide high-contrast parametric image sets of lower dimensions than the original data set separating structures based on their kinetic characteristics. Our method has the potential to constitute an alternative quantification method, independent of any kinetic model, and is particularly useful when the retrieval of the arterial input function is complicated. In independent component analysis images, structures that have different kinetic characteristics are assigned opposite values, and are readily discriminated. Furthermore, novel similarity mapping techniques are proposed, which can summarize in a single image the temporal properties of the entire image sequence according to a reference region. Results: Using our new cubed sum coefficient similarity measure, we have shown that structures with similar time activity curves can be identified, thus facilitating the detection of lesions that are not easily discriminated using the conventional method employing standardized uptake values.
Internacional
Si
JCR del ISI
No
Título de la revista
Biomed. Eng. online
ISSN
1475-925X
Factor de impacto JCR
0
Información de impacto
Volumen
6
DOI
Número de revista
36
Desde la página
1
Hasta la página
13
Mes
OCTUBRE
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • autor: T. Thireou (National Technical University of Athens)
  • Autor: Georgios Kontaxakis Antoniadis (UPM)
  • autor: S. Pavlopoulos (National Technical University of Athens)
  • Autor: Andres de Santos Lleo (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Tecnología de imágenes biomédicas
  • Departamento: Ingeniería Electrónica
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