Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Non-Rigid Motion Compensation in MR Prostate Perfusion Imaging
Year:2010
Research Areas
  • Electronic technology and of the communications
Information
Abstract
Prostate cancer (PCa) is currently the most frequently diagnosed non-cutaneous cancer and the second most important reason for cancer mortality in men. Early diagnosis is imperative as cure can often be established. Dynamic Contrast enhance MRI (DCE-MRI) has been established as accurate method in detection and localization of PCa. DCE-MRI is performed by obtaining repeated, fast T1-weighted images before and up to a few minutes after intravenous injection of a gadolinium containing contrast agent. Three-dimensional datasets of the prostate are obtained every few seconds. This allows obtaining a per-voxel signal-intensity vs. time curve. From this, different pharmacokinetic parameters are modeled and used to differentiate cancerous from non-cancerous tissue. Drawbacks are that rectal peristalsis and patient movement often result in spatial-mismatching of serial 3D datasets and therefore incorrect enhancement curves and pharmacokinetic parameters. Hence, a definite need exists to correct these movement related inaccuracies. Therefore, in this work we present a new algorithm that exploits temporal movement patterns to compensate for this movement and enable a more reliable and automatic analysis of the pharmacokinetic data.
International
Si
Congress
Joint Annual Meeting ISMRM-ESMRMB (International Society for Magnetic Resonance in Medicine - European Society for Magnetic Resonance in Medicine and Biology)
960
Place
Estocolmo (Suecia)
Reviewers
Si
ISBN/ISSN
1545-4428
Start Date
01/05/2010
End Date
07/05/2010
From page
0
To page
0
2010 SCIENTIFIC MEETING PROCEEDINGS
Participants
  • Autor: Gert Wöllny . (UPM)
  • Autor: Thomas Hambrock (Radboud University Nijmegen Medical Centre)
  • Autor: Andres de Santos Lleo (UPM)
  • Autor: Maria Jesus Ledesma Carbayo (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Tecnología de imágenes biomédicas
  • Departamento: Ingeniería Electrónica
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
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