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Descripción
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| YODA (YDA) is a MAPK kinase kinase (MAP3K) that functions downstream the Receptor Like Kinase (RLK) ERECTA (ER). YDA-ER pathway control Arabidopsis immune responses, but also stomatal patterning and other plant developmental-associated processes. Remarkably, plants expressing a constitutively active form of YDA (CA-YDA) show broad-spectrum disease resistance to different type of pathogens, including fungi, oomycetes, and bacteria. CA-YDA-mediated resistance is independent of defensive pathways regulated by salicylic acid, jasmonic acid or ethylene, and of previously characterised canonical immune pathways activated by Microbe-Associated Molecular Patterns (MAMPs). Comparative transcriptomic analyses of mock and fungal-inoculated wild-type and CA-YDA plants revealed that CA-YDA plants constitutively express a set of defense-associated genes, which encoded uncharacterised RLKs and putative extracellular peptides (ePEPs). We selected Arabidopsis mutants impaired in the expression of these ePEPs and tested their contribution to resistance against the fungal pathogen Plectosphaerella cucumerina BMM, the bacterium Pseudomonas syringae pv. tomato DC3000 and the oomycete Hyaloperonospora arabidopsidis Noco2. Remarkably, we found that some of these peptides contribute to Arabidopsis immunity since ePEPs mutants showed enhanced susceptibility to these pathogens. ER-YDA define a novel immune pathway that orchestrates broad-spectrum resistance by regulating defensive responses that act in parallel to canonical disease resistance pathways. We propose that plants evolutionarily co-opted the ER-YDA pathway to generate a novel immune surveillance system linked to stomata development, since these plant apertures are pathogen entry points. | |
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Internacional
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Si |
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Nombre congreso
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Plant Peptides & Receptors 2016 |
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Tipo de participación
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970 |
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Lugar del congreso
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Bischoffsheim,+France |
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Revisores
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Si |
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ISBN o ISSN
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0000-0000 |
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DOI
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Fecha inicio congreso
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31/08/2016 |
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Fecha fin congreso
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02/09/2016 |
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Desde la página
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0 |
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Hasta la página
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0 |
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Título de las actas
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Plant Peptides & Receptors 2016 |