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Memorias de investigación
Ponencias en congresos:
Characterizing And Extracting the Synaptic Apposition Surface For the Analysis of Synaptic Geometry
Año:2011
Áreas de investigación
  • Informática aplicada
Datos
Descripción
Studying the geometry of synaptic junctions enables new hy- potheses to be established regarding chemical communication between neurons. Morphological studies of these structures is greatly facilitated by the use of recent electron microscopy techniques that permit 3D re- construction of large numbers of synapses. Two critical components of the synaptic junction are the active zone and the postsynaptic density, as they are directly related to the synaptic release probability and the num- ber of postsynaptic receptors, respectively. Given that these two struc- tures are in close apposition, they can be represented by a single surface, the synaptic apposition surface. We have developed a technique to auto- matically extract this surface and the features of this structure that are most relevant to researchers interested in studying synaptic function.
Internacional
Si
Nombre congreso
5th Workshop on Data Mining in Functional Genomics and Proteomics: current trends and future directions
Tipo de participación
960
Lugar del congreso
Atenas, Grecia
Revisores
Si
ISBN o ISSN
DOI
Fecha inicio congreso
05/09/2011
Fecha fin congreso
05/09/2011
Desde la página
63
Hasta la página
72
Título de las actas
Proc. of the 5th Workshop on Data Mining in Functional Genomics and Proteomics: current trends and future directions
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Juan Morales Del Olmo (UPM)
  • Autor: Angel Rodriguez Mtnez.de Bartolome (UPM)
  • Autor: José Rodrigo-Rodríguez (CSIC)
  • Autor: Javier De Felipe Oroquieta (UPM)
  • Autor: Angel Merchan Perez (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Departamento: Arquitectura y Tecnología de Sistemas Informáticos
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