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Descripción
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| Alt a 1 is a protein found in Alternaria alternata spores related to virulence and pathogenicity and considered to be responsible for chronic asthma in children. We found that spores of Alternaria inoculated on the outer surface of kiwifruits did not develop hyphae. Nevertheless, the expression of Alt a 1 gene was upregulated, and the protein was detected in the pulp where it co-localized with kiwi PR5. Pull-down assays demonstrated experimentally that the two proteins interact in such a way that Alt a 1 inhibits the enzymatic activity of PR5. These results are relevant not only for plant defense, but also for human health as patients with chronic asthma could suffer from an allergic reaction when they eat fruit contaminated with Alternaria. | |
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Internacional
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Si |
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JCR del ISI
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Si |
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Título de la revista
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Febs Letters |
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ISSN
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0014-5793 |
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Factor de impacto JCR
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3,341 |
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Información de impacto
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Volumen
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DOI
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Número de revista
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Desde la página
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1501 |
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Hasta la página
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1508 |
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Mes
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SIN MES |
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Ranking
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