Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Functional Hubs in Mild Cognitive Impairment
Año:2015
Áreas de investigación
  • Ciencias naturales y ciencias de la salud
Datos
Descripción
We investigate how hubs of functional brain networks are modified as a result of mild cognitive impairment (MCI), a condition causing a slight but noticeable decline in cognitive abilities, which sometimes precedes the onset of Alzheimer's disease. We used magnetoencephalography (MEG) to investigate the functional brain networks of a group of patients suffering from MCI and a control group of healthy subjects, during the execution of a short-term memory task. Couplings between brain sites were evaluated using synchronization likelihood, from which a network of functional interdependencies was constructed and the centrality, i.e. importance, of their nodes was quantified. The results showed that, with respect to healthy controls, MCI patients were associated with decreases and increases in hub centrality respectively in occipital and central scalp regions, supporting the hypothesis that MCI modifies functional brain network topology, leading to more random structures.
Internacional
Si
JCR del ISI
Si
Título de la revista
International Journal of Bifurcation and Chaos
ISSN
0218-1274
Factor de impacto JCR
1,078
Información de impacto
Volumen
25
DOI
10.1142/S0218127415500340
Número de revista
3
Desde la página
1550034-1
Hasta la página
1550034-10
Mes
MARZO
Ranking
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Participantes
  • Autor: Adrian Navas Santo-Tomas (UPM)
  • Autor: David Papo . (UPM)
  • Autor: Stefano Boccaletti (UPM)
  • Autor: Francisco del-Pozo (UPM)
  • Autor: Ricardo Bajo Breton (UPM)
  • Autor: Fernando Maestu Unturbe (UPM)
  • Autor: Johann Heinz Martínez (UPM)
  • Autor: Pablo Aguilar Gil (UPM)
  • Autor: Irene Sendiá-Nadal (URJC)
  • Autor: Javier Martín Buldú (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Departamento: Tecnología Fotónica y Bioingeniería
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