Observatorio de I+D+i UPM

Memorias de investigación
Conferencias:
NITROGENASE ASSEMBLY IN EUKARYOTES
Año:2015
Áreas de investigación
  • Ciencias naturales y ciencias de la salud
Datos
Descripción
The extensive use of synthetic N fertilizers in developed countries poses enormous environmental threats that must be addressed. The awareness that biological N2 fixation can be used as alternative to the synthetic N fertilizers in the implementation of modern sustainable agricultural practices is an underlying driving force for nitrogenase studies. An ambitious challenge of plant biotechnology is to increase cereal crop productivity by engineering plants to fix their own nitrogen, i.e. by functional expression of bacterial N2 fixation (nif) genes in the plant.1,2 Two identified barriers have traditionally impaired this approach: the known sensitivity of nitrogenase to O2 (the byproduct of plant photosynthesis) and the genetic/biochemical complexity of nitrogenase biosynthesis. Balanced expression of at least 9 nif gene is required to mature nitrogenase structural polypeptides into their catalytically active forms.3 Both nitrogenase components, as well as most proteins required for the assembly of their metal clusters, are very sensitive to O2. The initial hypothesis of this work is that the mitochondrial matrix could provide a low O2 environment appropriate for the assembly and the activity of nitrogenase components. Advances towards obtaining proof of concept for this hypothesis will be presented.
Internacional
Si
ISSN o ISBN
000000000
Entidad relacionada
19TH INTERNATIONAL CONFERENCE ON NITROGEN FIXATION
Nacionalidad Entidad
Sin nacionalidad
Lugar del congreso
Pacific Grove (CA). EE.UU.
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Gema Lopez Torrejon (UPM)
  • Autor: Emilio Jimenez Vicente (UPM)
  • Autor: José María Buesa Galiano (UPM)
  • Autor: Luis Manuel Rubio Herrero (UPM)
  • Autor: Jose A. Hernandez (Midwestern University)
  • Autor: Hemant K. Verma (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: BIOLOGÍA MOLECULAR Y COMPUTACIONAL
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología - Biología Vegetal
S2i 2021 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
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