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Descripción
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| he study of healthy and pathological aging with magnetoencephalography (MEG) has become more widespread in recent years. This is mainly because it is providing a new perspective in the study of this disease. Its excellent temporal resolution allows the evaluation of functional networks in the frequency domain. These characteristics make MEG unique for the study of the organization of the neurophysiological mechanisms supporting cognitive capabilities in the aging brain. In this chapter, we will review MEG findings in normal and pathological aging. In normal aging, we will go through the mechanisms of forgetting and the assessment of the default mode network organization. In the field of pathological aging, the literature has mainly focused on Alzheimer's Disease (AD). These studies assess sensory memory, short-term and long-term memory, indicating decreased activity and connectivity in AD patients but a dual pattern of increased/decreased functional connectivity at early stages such as mild cognitive impairment (MCI) or subjective cognitive decline (SCD). Finally, similar results have been found in an extensive literature using resting state recordings which characterize the brain networks of patients with dementia in a non-task context. All these topics will be discussed in the context of the literature of cognitive neuroscience of aging. Potential new approaches and recommendations for future research will be provided. © Springer Nature Switzerland AG 2019. All rights are reserved. | |
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Internacional
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Si |
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DOI
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10.1007/978-3-030-00087-5_28 |
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Edición del Libro
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2 |
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Editorial del Libro
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Springer International Publishing |
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ISBN
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978-303000086-8 |
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Serie
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Título del Libro
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Magnetoencephalography: From Signals to Dynamic Cortical Networks: Second Edition |
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Desde página
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817 |
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Hasta página
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851 |