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Memorias de investigación
Artículos en revistas:
List-mode-based Reconstruction for Respiratory Motion Correction in PET using Non-rigid Body Transformations
Año:2007
Áreas de investigación
  • Industria electrónica
Datos
Descripción
Respiratory motion in emission tomography leads to reduced image quality. Developed correction methodology has been concentrating on the use of respiratory synchronized acquisitions leading to gated frames. Such frames, however, are of low signal-to-noise ratio as a result of containing reduced statistics. In this work, we describe the implementation of an elastic transformation within a list-mode-based reconstruction for the correction of respiratory motion over the thorax, allowing the use of all data available throughout a respiratory motion average acquisition. The developed algorithm was evaluated using datasets of theNCAT phantom generated at different points throughout the respiratory cycle. List-mode-data-based PET-simulated frames were subsequently produced by combining the NCAT datasets with Monte Carlo simulation. A non-rigid registration algorithm based on B-spline basis functions was employed to derive transformation parameters accounting for the respiratory motion using the NCAT dynamic CT images. The displacement matrices derived were subsequently applied during the image reconstruction of the original emission list mode data. Two different implementations for the incorporation of the elastic transformations within the one-pass list mode EM(OPL-EM) algorithm were developed and evaluated. The corrected images were compared with those produced using an affine transformation of list mode data prior to reconstruction, as well as with uncorrected respiratory motion average images. Results demonstrate that although both correction techniques considered lead to significant improvements in accounting for respiratory motion artefacts in the lung fields, the elastic-transformation-based correction leads to a more uniform improvement across the lungs for different lesion sizes and locations.
Internacional
Si
JCR del ISI
Si
Título de la revista
PHYS MED BIOL
ISSN
0031-9155
Factor de impacto JCR
2,528
Información de impacto
Volumen
52
DOI
Número de revista
17
Desde la página
5187
Hasta la página
5204
Mes
SEPTIEMBRE
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Participantes
  • autor: A.J. Reader (LaTIM, Brest, France)
  • autor: T. Cresson (LaTIM, Brest, France)
  • autor: D. Visvikis (LaTIM, Brest, France)
  • Autor: Georgios Kontaxakis Antoniadis (UPM)
  • Autor: Andres de Santos Lleo (UPM)
  • autor: C. Cheze Le Rest (LaTIM, Brest, France)
  • Autor: Maria Jesus Ledesma Carbayo (UPM)
  • autor: F. Lamare (LaTIM, Brest, France)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Tecnología de imágenes biomédicas
  • Departamento: Ingeniería Electrónica
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